Can we answer every question?

I read Stephen Wolfram's A New Kind of Science awhile back (and absorbed some of it), and along with Hofstadter's Goedel, Escher, Bach, Dawkins' The Selfish Gene, Penrose's The Road to Reality, Dennet's Consciousness Explained, and many of Asimov's nonfiction and fiction (ideas like laws of robotics and psychohistory), along with of course a myriad of other books, from Cosmology, Number Theory, Philosophy, Neurology, Logic, History, Artificial Intelligence, Network Theory, Information Theory, Topology, Complexity, Chaos, Emergence, Fractals, Memetics, and so on, I've developed my own overall ideas (I won't be presumptuous enough to call them theories, maybe hypotheses though, where they can be tested in reality) on some of the "big picture" truths about the world we live in.

Here is Wolfram giving a brief talk at this year's TED (I highly recommended all of TED's vast archive of talks, by the way, to any thinking person) about "computational knowledge."